To study for several malignancy-associated changes in the cervical tissues around squamous cell carcinoma of the female uterine cervix, which is most frequent malignancy in the Korean females, 180 cases of squamous cell carcinoma, collected from 1975 to 1979 at the Department of Pathology, Chungnam National University School of Medicine, were compared with cancer-associated changes between carcinoms in situ and invasive-carcinoma, and among types of invasive carcinoma.
The results observed were as follows:
1. Dysplasia, which is thought of precursor of cervical carcinoma of the uterine cervix, was the most frequent and severe degree in poorly differentiated carcinoma and lowest frequency and mild degree in well differentiated carcinoma.
2. Squamous metaplasia was most frequent in carcinoma in situ, and the lowest in well differentiated type of invasive carcinoma.
3. The epithelial hyperplastic changes in the uterine cervix revealed the most frequent in carcinoma in situ, and the lowest in the poorly differentiated type of carcinoma.
4. Inflammatory lesions were the most frequent and severe in poorly differentiated type of carcinoma, and the lowest and mild in well differentiated type of carcinoma.
5. Retrogressive changes and erosion of the cervix revealed the most frequent and severe in poorly differentiated type of carcinoma, and the lowest and mild in well differentiated type of carcinoma.
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